Sam received her BS in biomedical science at Imperial College London, studying infectious diseases. She then worked as a technician for a year in Bruno Reversade's laboratory before ending up at HMS. Her current work examines the enzymology of prolyl hydroxylase 3 and its role in lipid metabolism.
Sarah completed her undergraduate studies at the University of Illinois Urbana-Champaign. Her undergraduate research in the laboratory of Martin Burke was focused on synthesizing less toxic derivatives of antifungal natural products. She is currently interested in understanding mitochondrial sirtuin activity and substrate specificity in the context of metabolic diseases. Her work is supported by a fellowship from Joslin Diabetes Center.
Favorite alpaca name: Alpacino
Giulia completed her undergraduate studies at Mount Holyoke College. After graduating, she spent two years at the NIH in the lab of Michael Lenardo, working on understanding the molecular mechanisms that control cellular responses, and how defects in such responses may lead to diseases of the immune system. She is currently interested in characterizing tumor-immune metabolic interactions in the tumor microenvironment.
Jefte's work, mentored by Marcia Haigis and Arlene Sharpe, focuses on the metabolic regulation of T cell functionality, particularly in the context of immune responses against cancer. He is supported by a fellowship from the National Institutes of Health.
Has a love-hate relationship with: chocolate (it's complicated).
I am interested in the adaptive reprogramming of cancer cells under the selective pressure imposed by therapeutics that enriches the microenvironment with resistant cells. Specifically, I am interested in understanding the metabolic requirements that support this transition. My work is supported by the National Science Foundation Grad
I’m interested in studying the role of mitochondrial sirtuins in governing mitochondrial fate from a quality control viewpoint. My work is supported by a PhD grant from the Portuguese Foundation for Science and Technology (FCT).
My project focuses on the role of mitochondrial sirtuins on glutamine metabolism. Like Natalie, I am in the Biological and Biomedical Sciences Program at HMS. I enjoy spending time with friends and family. I also like to dance, travel, crochet, learn new languages, and I am open to trying and learning new things. My work is supported by The Paul & Daisy Soros Fellowship for New Americans.
Jaewon is studying the pathways that (mitochondrial) sirtuins regulate in response to various cell stress signals. He is currently attending Tufts University School of Medicine, has received a summer Proctor Program Award, and is supported by a HHMI Medical Research Fellows Program received in 2012.
Having completed his PhD in our lab on the regulation of SIRT3 expression, Kyle is currently conducting a small molecule screen for activators of mitochondrial function. His work is supported by the Blavatnik Biomedical Accelerator.
I recently completed my PhD in the Haigis lab with a dissertation focused on identifying and exploiting metabolic vulnerabilities in cancer. Now as a post-doc, I am finishing my research on nutrient utilization and metabolic liabilities in acute myeloid leukemia.